魏嘉，中共党员，博士研究生学历，伟德国际bevictor1946附属鼓楼医院副经理，主任医师/教授，博士生导师，bv1946伟德官网临床肿瘤研究所副所长，教育部“长江学者奖励计划”青年学者，科技部科技重大专项首席科学家，哈佛大学伟德国际bevictor1946/麻省总医院/Dana-Farber癌症中心fellow，中国肿瘤青年科学家。

中国抗癌协会整合肿瘤学分会副主任委员

中国临床肿瘤学会（CSCO）青年专家委员会副主任委员

中国青年科技工作者协会委员

中国抗癌协会青年理事会常务理事

江苏省政协委员

江苏省欧美同学会副会长

1)      Shi T, Wei J. Targeting DKK1 to Remodel the Tumor Microenvironment and Enhance Immune Checkpoint Blockade Therapy. J Clin Oncol. 2025 Jan 20;43(3):350-353.(IF：42.1，1区) (通讯)

2)      Wei J, Lu X, Liu Q, Fu Y, Liu S, Zhao Y, Zhou J, Chen H, Wang M, Li L, Yang J, Liu F, Zheng L, Yin H, Yang Y, Zhou C, Zeng P, Zhou X, Ding N, Chen S, Zhao X, Yan J, Fan X, Guan W, Liu B. Neoadjuvant sintilimab in combination with concurrent chemoradiotherapy for locally advanced gastric or gastroesophageal junction adenocarcinoma: a single-arm phase 2 trial. Nat Commun. 2023 Aug 14;14(1):4904.(IF:14.7，1区) (第一作者)

3)      Liu Q, Chu Y, Shao J, Qian H, Yang J, Sha H, Cen L, Tian M, Xu Q, Chen F, Yang Y, Wang W, Wang K, Yu L, Wei J, Liu B. Benefits of an Immunogenic Personalized Neoantigen Nanovaccine in Patients with High-Risk Gastric/Gastroesophageal Junction Cancer. Adv Sci (Weinh). 2022 Nov 9;10(1):e2203298. (IF:15.1，1区)（共同通讯）

4)      Chen H*, Shi T*, Wang Y, Liu Z, Liu F, Zhang H, Wang X, Miao Z, Liu B, Wan M#, Mao C, Wei J#. Deep Penetration of Nanolevel Drugs and Micrometer-Level T Cells Promoted by Nanomotors for Cancer Immunochemotherapy. J Am Chem Soc. 2021 Aug 11;143(31):12025-12037. (IF：15.419，1区) (共同通讯)

5)      Pan Y, Xue Q, Yang Y, Shi T, Wang H, Song X, Luo Y, Liu W, Ren S, Cai Y, Nie Y, Song Z, Liu B, Li JP, Wei J. Glycoengineering-based anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy through T cell engagement. Cell Rep Med. 2024 Jun 18;5(6):101590.(IF:11.7，1区)(共同通讯)

6)      Shi T, Zhang Y, Wang Y, Song X, Wang H, Zhou X, Liang K, Luo Y, Che K, Wang X, Pan Y, Liu F, Yang J, Liu Q, Yu L, Liu B, Wei J. DKK1 Promotes Tumor Immune Evasion and Impedes Anti-PD-1 Treatment by Inducing Immunosuppressive Macrophages in Gastric Cancer. Cancer Immunol Res. 2022 Dec 2;10(12):1506-1524. (IF：12.02，1区) (通讯作者)

7)      Che K, Luo Y, Song X, Yang Z, Wang H, Shi T, Wang Y, Wang X, Wu H, Yu L, Liu B, Wei J. Macrophages reprogramming improves immunotherapy of IL-33 in peritoneal metastasis of gastric cancer. EMBO Mol Med. 2024 Feb;16(2):251-266.(IF: 9.0，1区) (通讯作者)

8)      Wang Y, Wang H, Shi T, Song X, Zhang X, Zhang Y, Wang X, Che K, Luo Y, Yu L, Liu B, Wei J. Immunotherapies targeting the oncogenic fusion gene CLDN18-ARHGAP in gastric cancer. EMBO Mol Med. 2024 Sep;16(9):2170-2187.(IF: 9.0，1区) (通讯作者)

9)      Chen F, Zou Z, Du J, Su S, Shao J, Meng F, Yang J, Xu Q, Ding N, Yang Y, Liu Q, Wang Q, Sun Z, Zhou S, Du S, Wei J, Liu B. Neoantigen identification strategies enable personalized immunotherapy in refractory solid tumors. J Clin Invest. 2019 Mar 5;129(5):2056-2070. doi: 10.1172/JCI99538.  (IF：19.456，1区) (共同通讯)

10)    Ding N, Zou Z, Sha H, Su S, Qian H, Meng F, Chen F, Du S, Zhou S, Chen H, Zhang L, Yang J, Wei J, Liu B. iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric cancer. Nat Commun. 2019 Mar 22;10(1):1336. (IF:17.694，1区) (共同通讯)

  研究方向为恶性肿瘤个体化靶向/免疫治疗，主持科技部“重大新药创制”科技重大专项及多项国家自然科学基金。

相关研究获教育部科技进步奖、中华医学科技奖、江苏省科学技术进步奖等省部级奖励14项。